Free consultation
& full technical support at every stage of
your entire testing and reporting progress from
our technical staff and scientists.
After your sample reaches our laboratory,
DNA testing begins immediately on the same day that the samples
are received. The DNA test usually takes approximately 5 working
days to complete. The testing process can be divided into
4 major stages.
Step 1 -
DNA Isolation, Quantitation, and Purification
During this stage, the laboratory isolates the
buccal cells from the head of the swabs. After removing the
cells from the swabs, the DNA is extracted from the cells. The
DNA is quantitated to determine how much DNA is present and
the DNA is further concentrated and purified if required.
Step 2 -
PCR Amplification
During this stage, the laboratory amplifies
specific regions of your DNA for further examination. The DNA
is amplified by a process known as PCR (stands for Polymerase
Chain Reaction). PCR is a very powerful technique which can
amplify a single strand of DNA over a million fold in very little
time. PCR is a very sensitive technique and is frequently used
in forensic laboratories to analyze blood stains, hair, and
saliva stains.
Step 3 -
Sequencing
Sequencing allows the laboratory to examine
the DNA once it has been amplified by PCR. There are different
methods available to detect the amplified DNA. In smaller laboratories,
sequencing is often performed manually and is prone to human
error. In larger laboratories, sequencing is fully automated.
Automated sequencing is fast and very precise. At Genex, sequencing
is performed using the latest and most advanced automated sequencers
to ensure the most accurate results possible. During sequencing,
the DNA fragments are passed through a matrix and detected by
lasers. The detected fragments and their properties are then
output to a computer for analysis.
Step 4 -
Analysis
The final step of the testing process is the
analysis of the genetic information. Each and every gene that
was examined is fully documented in your final report. If the
alleged father is not the true biological father of the child,
the alleged father's DNA will not match the half of the child's
genetic material which came from the father. If the test man
is indeed the true biological father of the child, the paternal
half of the genetic material of the child will match that of
the alleged father's perfectly. Depending on the race of the
tested individuals, a paternity index is generated to determine
probability of paternity. At Genex, we examine 16 genetic locations
for each individual and we guarantee absolutely conclusive results
for every test. All exclusions are 100% and inclusions exceed
99.999%. You will never receive an inconclusive answer.
