How Do We Perform Paternity Testing?
We understand how important it is to get your DNA test results quickly and accurately. That’s why our lab team begins the testing process immediately after we receive your samples. The testing process can be divided into 4 major stages.
Step 1 – DNA Isolation, Quantitation, and Purification
During the first stage, the laboratory isolates the buccal (cheek) cells from the swabs and extracts the DNA. The DNA is then quantitated to determine the amount present and further concentrated and purified if necessary.
Step 2 – DNA Amplification
In the second stage, the laboratory uses a powerful technique called polymerase chain reaction (PCR) to amplify the DNA over a million-fold in a short amount of time. PCR is frequently used in forensic laboratories to analyze blood stains, hair, and saliva stains.
Step 3 – Sequencing
Sequencing is the process of determining the specific order of nucleotides within a strand of DNA. This step is usually performed manually in smaller laboratories, but is typically done using automated sequencing in larger laboratories. Automated sequencing is faster and more precise than manual methods. At Genex, we use the most advanced automated sequencers to guarantee accurate results. During sequencing, the DNA fragments pass through a matrix and are detected by lasers. These fragments and their properties are then transferred to a computer for further analysis.
Step 4 – Analysis
The final step of a paternity test is analyzing the genetic information provided. This process helps determine whether or not the person being tested is the true biological father of the child. If the alleged father is the biological father, their DNA will match perfectly with the child’s genetic material. Our exclusions are 100% accurate and our inclusions exceed 99.9%. You can be confident that you will receive a conclusive answer from our paternity test.